Anal cancer rate survival
Anal cancer is a rare malignancy with approximately 5, new cases diagnosed annually in the United States. As a result of carefully conducted epidemiologic and clinical studies, it is now established that anal cancer is closely associated with human papillomavirus HPV infection. The cure of anal cancer is possible in the majority of patients with preservation of the anal sphincter. This malignancy has been historically treated by abdominoperineal resection, with associated high rates of morbidity and local recurrence. Pioneering work by Nigro a surgeon led to the discovery that radiation therapy combined with the drugs 5-fluorouracil 5-FU and mitomycin resulted in high rates of local control, disease-free, colostomy-free and overall survival without surgical intervention.
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Anal Cancer: An Overview
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Radiotherapy with concurrent chemotherapy is the standard of care for patients with nonmetastatic squamous cell anal cancer. Most patients treated with chemoradiotherapy have an excellent prognosis. However, some heterogeneity exists among anal cancer patients in their outcomes. This article reviews some of the clinical factors, treatment-related factors, and biologic factors that affect outcomes in patients with squamous cell anal cancer. The most important prognostic factors are the T and N stages. Some studies have suggested that women have better prognosis than men.
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Anal Cancer Survival Rates
Skip to Content. You will also read general information on surviving the disease. Remember, survival rates depend on several factors. Use the menu to see other pages. This year, an estimated 8, adults 2, men and 5, women in the United States will be diagnosed with anal cancer.
Anal cancer is a rare tumor with an incidence that has been rising over the last 25 years. The disease was once thought to develop as a result of chronic irritation, but it is now known that this is not the case. Multiple risk factors, including human papillomavirus HPV infection, anoreceptive intercourse, cigarette smoking, and immunosuppression, have been identified.
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